AustralieFrV1, Main, Exploration, bibRecord, 008E75

Angular (Gothic) aortic arch leads to enhanced systolic wave reflection, central aortic stiffness, and increased left ventricular mass late after aortic coarctation repair : Evaluation with magnetic resonance flow mapping

Identifieur interne : 008E75 ( Main/Exploration ); précédent : 008E74; suivant : 008E76

Angular (Gothic) aortic arch leads to enhanced systolic wave reflection, central aortic stiffness, and increased left ventricular mass late after aortic coarctation repair : Evaluation with magnetic resonance flow mapping

Auteurs : Phalla Ou [France] ; David S. Celermajer [Australie] ; Olivier Raisky [France] ; Odile Jolivet [France] ; Fanny Buyens [France] ; Alain Herment [France] ; Daniel Sidi [France] ; Damien Bonnet [France] ; Elie Mousseaux [France]

Source :

Journal of thoracic and cardiovascular surgery [ 0022-5223 ] ; 2008.

RBID : Pascal:08-0305537

Descripteurs français

Pascal (Inist)
- Tumeur, Coarctation aortique, Arc aortique, Plomb, Onde, Aorte, Rigidité, Ventricule gauche, Masse, Tardif, Réparation, Chirurgie correctrice, Traitement, Evaluation, Imagerie RMN, Résonance magnétique, Cartographie, Carte génétique, Anesthésie, Appareil circulatoire, Cardiologie.
Wicri :
- topic : Plomb, Cartographie.

English descriptors

KwdEn :
- Anesthesia, Aorta, Aortic arch, Aortic coarctation, Cardiology, Cartography, Circulatory system, Corrective surgery, Evaluation, Genetic mapping, Late, Lead, Left ventricle, Magnetic resonance, Mass, Nuclear magnetic resonance imaging, Repair, Stiffness, Treatment, Tumor, Wave.

Abstract

Objective: We sought to investigate the mechanism whereby a particular deformity of the aortic arch, an angulated Gothic shape, might lead to hypertension late after anatomically successful repair of aortic coarctation. Methods: Fifty-five normotensive patients with anatomically successful repair of aortic coarctation and either a Gothic (angulated) or a Romanesque (smooth and rounded) arch were studied with magnetic resonance angiography and flow mapping in both the ascending and descending aortas. Systolic waveforms, central aortic stiffness, and pulse velocity were measured. We hypothesized that arch angulation would result in enhanced systolic wave reflection with loss of energy across the aortic arch, as well as increased central aortic stiffness. Results: Twenty patients were found to have a Gothic, and 35 a Romanesque, arch. Patients with a Gothic arch showed markedly augmented systolic wave reflection (12 ± 6 vs 5 ± 0.3 mL, P <.001) and greater loss of systolic wave height in the distal aorta (30% ± 16% vs 22% ± 12%, P <.01) compared with that of subjects with a Romanesque arch. Pulse wave velocity was also increased with a Gothic arch (5.6 ± 1.1 vs 4.1 ± 1 m/s, P <.0001), as well as left ventricular mass index (85 ± 15 vs 77 ± 20 g/m²). Patients with a Romanesque arch had increased aortic stiffness compared with that of control subjects (stiffness β-index, 3.9 ± 0.9 vs 2.9 ± 1; P =.03). Conclusions: Angulated Gothic aortic arch is associated with increased systolic wave reflection, as well as increased central aortic stiffness and left ventricular mass index. These findings explain (at least in part) the association between this pattern of arch geometry and late hypertension at rest and on exercise in subjects after coarctation repair.

Affiliations:

Links toward previous steps (curation, corpus...)

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Le document en format XML

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<author><name sortKey="Herment, Alain" sort="Herment, Alain" uniqKey="Herment A" first="Alain" last="Herment">Alain Herment</name>
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<author><name sortKey="Sidi, Daniel" sort="Sidi, Daniel" uniqKey="Sidi D" first="Daniel" last="Sidi">Daniel Sidi</name>
<affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Department of Pediatric Cardiology, UFR Necker-Enfants Malades, University Rene Descartes Paris V,AP-HP</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>7 aut.</sZ>
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<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
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<author><name sortKey="Bonnet, Damien" sort="Bonnet, Damien" uniqKey="Bonnet D" first="Damien" last="Bonnet">Damien Bonnet</name>
<affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Department of Pediatric Cardiology, UFR Necker-Enfants Malades, University Rene Descartes Paris V,AP-HP</s1>
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<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
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<author><name sortKey="Mousseaux, Elie" sort="Mousseaux, Elie" uniqKey="Mousseaux E" first="Elie" last="Mousseaux">Elie Mousseaux</name>
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<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="06"><s1>Department of Cardiovascular Radiology, Hôpital Européen Georges Pompidou, University Rene Descartes Paris V, AP-HP</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>9 aut.</sZ>
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<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
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<series><title level="j" type="main">Journal of thoracic and cardiovascular surgery</title>
<title level="j" type="abbreviated">J. thorac. cardiovasc. surg.</title>
<idno type="ISSN">0022-5223</idno>
<imprint><date when="2008">2008</date>
</imprint>
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<seriesStmt><title level="j" type="main">Journal of thoracic and cardiovascular surgery</title>
<title level="j" type="abbreviated">J. thorac. cardiovasc. surg.</title>
<idno type="ISSN">0022-5223</idno>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anesthesia</term>
<term>Aorta</term>
<term>Aortic arch</term>
<term>Aortic coarctation</term>
<term>Cardiology</term>
<term>Cartography</term>
<term>Circulatory system</term>
<term>Corrective surgery</term>
<term>Evaluation</term>
<term>Genetic mapping</term>
<term>Late</term>
<term>Lead</term>
<term>Left ventricle</term>
<term>Magnetic resonance</term>
<term>Mass</term>
<term>Nuclear magnetic resonance imaging</term>
<term>Repair</term>
<term>Stiffness</term>
<term>Treatment</term>
<term>Tumor</term>
<term>Wave</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Tumeur</term>
<term>Coarctation aortique</term>
<term>Arc aortique</term>
<term>Plomb</term>
<term>Onde</term>
<term>Aorte</term>
<term>Rigidité</term>
<term>Ventricule gauche</term>
<term>Masse</term>
<term>Tardif</term>
<term>Réparation</term>
<term>Chirurgie correctrice</term>
<term>Traitement</term>
<term>Evaluation</term>
<term>Imagerie RMN</term>
<term>Résonance magnétique</term>
<term>Cartographie</term>
<term>Carte génétique</term>
<term>Anesthésie</term>
<term>Appareil circulatoire</term>
<term>Cardiologie</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Plomb</term>
<term>Cartographie</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Objective: We sought to investigate the mechanism whereby a particular deformity of the aortic arch, an angulated Gothic shape, might lead to hypertension late after anatomically successful repair of aortic coarctation. Methods: Fifty-five normotensive patients with anatomically successful repair of aortic coarctation and either a Gothic (angulated) or a Romanesque (smooth and rounded) arch were studied with magnetic resonance angiography and flow mapping in both the ascending and descending aortas. Systolic waveforms, central aortic stiffness, and pulse velocity were measured. We hypothesized that arch angulation would result in enhanced systolic wave reflection with loss of energy across the aortic arch, as well as increased central aortic stiffness. Results: Twenty patients were found to have a Gothic, and 35 a Romanesque, arch. Patients with a Gothic arch showed markedly augmented systolic wave reflection (12 ± 6 vs 5 ± 0.3 mL, P <.001) and greater loss of systolic wave height in the distal aorta (30% ± 16% vs 22% ± 12%, P <.01) compared with that of subjects with a Romanesque arch. Pulse wave velocity was also increased with a Gothic arch (5.6 ± 1.1 vs 4.1 ± 1 m/s, P <.0001), as well as left ventricular mass index (85 ± 15 vs 77 ± 20 g/m<sup>2</sup>
). Patients with a Romanesque arch had increased aortic stiffness compared with that of control subjects (stiffness β-index, 3.9 ± 0.9 vs 2.9 ± 1; P =.03). Conclusions: Angulated Gothic aortic arch is associated with increased systolic wave reflection, as well as increased central aortic stiffness and left ventricular mass index. These findings explain (at least in part) the association between this pattern of arch geometry and late hypertension at rest and on exercise in subjects after coarctation repair.</div>
</front>
</TEI>
<affiliations><list><country><li>Australie</li>
<li>France</li>
</country>
<region><li>Nouvelle-Galles du Sud</li>
<li>Île-de-France</li>
</region>
<settlement><li>Paris</li>
<li>Sydney</li>
</settlement>
<orgName><li>Université de Sydney</li>
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<tree><country name="France"><region name="Île-de-France"><name sortKey="Ou, Phalla" sort="Ou, Phalla" uniqKey="Ou P" first="Phalla" last="Ou">Phalla Ou</name>
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<name sortKey="Bonnet, Damien" sort="Bonnet, Damien" uniqKey="Bonnet D" first="Damien" last="Bonnet">Damien Bonnet</name>
<name sortKey="Buyens, Fanny" sort="Buyens, Fanny" uniqKey="Buyens F" first="Fanny" last="Buyens">Fanny Buyens</name>
<name sortKey="Herment, Alain" sort="Herment, Alain" uniqKey="Herment A" first="Alain" last="Herment">Alain Herment</name>
<name sortKey="Jolivet, Odile" sort="Jolivet, Odile" uniqKey="Jolivet O" first="Odile" last="Jolivet">Odile Jolivet</name>
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   |wiki=    Wicri/Asie
   |area=    AustralieFrV1
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   |clé=     Pascal:08-0305537
   |texte=   Angular (Gothic) aortic arch leads to enhanced systolic wave reflection, central aortic stiffness, and increased left ventricular mass late after aortic coarctation repair : Evaluation with magnetic resonance flow mapping
}}

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	Serveur d'exploration sur les relations entre la France et l'Australie
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Serveur d'exploration sur les relations entre la France et l'Australie

Angular (Gothic) aortic arch leads to enhanced systolic wave reflection, central aortic stiffness, and increased left ventricular mass late after aortic coarctation repair : Evaluation with magnetic resonance flow mapping

Angular (Gothic) aortic arch leads to enhanced systolic wave reflection, central aortic stiffness, and increased left ventricular mass late after aortic coarctation repair : Evaluation with magnetic resonance flow mapping

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